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Tae Cheon Jeong Selected Research

Saponins

2/2015Saponins, especially platyconic acid A, from Platycodon grandiflorum reduce airway inflammation in ovalbumin-induced mice and PMA-exposed A549 cells.
7/2014Platycodon grandiflorum root-derived saponins attenuate atopic dermatitis-like skin lesions via suppression of NF-κB and STAT1 and activation of Nrf2/ARE-mediated heme oxygenase-1.
1/2014Saponins from the roots of Platycodon grandiflorum suppresses TGFβ1-induced epithelial-mesenchymal transition via repression of PI3K/Akt, ERK1/2 and Smad2/3 pathway in human lung carcinoma A549 cells.
12/2011Saponins from the roots of Platycodon grandiflorum suppress ultraviolet A-induced matrix metalloproteinase-1 expression via MAPKs and NF-κB/AP-1-dependent signaling in HaCaT cells.

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Tae Cheon Jeong Research Topics

Disease

18Neoplasms (Cancer)
01/2021 - 01/2004
11Inflammation (Inflammations)
10/2020 - 01/2009
8Hepatocellular Carcinoma (Hepatoma)
06/2014 - 12/2002
7Breast Neoplasms (Breast Cancer)
12/2019 - 10/2010
3Atopic Dermatitis (Atopic Eczema)
07/2014 - 03/2013
3Dermatitis
07/2014 - 03/2013
3Fibrosarcoma
05/2011 - 10/2010
2Colitis
12/2019 - 05/2018
2Pain (Aches)
09/2019 - 01/2015
2Body Weight (Weight, Body)
05/2018 - 12/2011
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2016 - 09/2013
2Neoplasm Metastasis (Metastasis)
01/2016 - 05/2011
2Carcinogenesis
10/2014 - 11/2011
2Cardiovascular Diseases (Cardiovascular Disease)
03/2014 - 11/2011
2Fibrosis (Cirrhosis)
01/2014 - 11/2013
2Carcinoma (Carcinomatosis)
01/2014 - 09/2013
1Muscle Spasticity (Spastic)
07/2020
1Migraine Disorders (Migraine)
07/2020
1Strabismus (Squint)
07/2020
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
05/2018
1Non-alcoholic Fatty Liver Disease
01/2018
1Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
08/2017
1Atherosclerosis
02/2016
1Vascular Diseases (Vascular Disease)
02/2016
1Alcoholic Liver Diseases (Alcoholic Liver Disease)
04/2015
1Allergic Contact Dermatitis
03/2015
1Osteoarthritis
01/2015
1Rheumatoid Arthritis
01/2015
1Colonic Neoplasms (Colon Cancer)
09/2014

Drug/Important Bio-Agent (IBA)

6Pharmaceutical PreparationsIBA
12/2019 - 01/2004
5Proteins (Proteins, Gene)FDA Link
01/2018 - 10/2010
5Messenger RNA (mRNA)IBA
08/2017 - 03/2013
5Cytochrome P-450 CYP1A1 (CYP1A1)IBA
10/2014 - 08/2004
4CytokinesIBA
05/2018 - 01/2009
4SaponinsIBA
02/2015 - 12/2011
3Polychlorinated Dibenzodioxins (TCDD)IBA
10/2014 - 12/2002
3Immunoglobulin E (IgE)IBA
07/2014 - 03/2013
3Dinitrochlorobenzene (DNCB)IBA
07/2014 - 03/2013
3Interleukin-13IBA
07/2014 - 03/2013
3Interleukin-5 (Interleukin 5)IBA
07/2014 - 03/2013
3Interleukin-4 (Interleukin 4)IBA
07/2014 - 03/2013
2Reactive Oxygen Species (Oxygen Radicals)IBA
12/2019 - 12/2002
2Biological ProductsIBA
12/2019 - 07/2014
2Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
01/2018 - 10/2014
2LeptinIBA
08/2017 - 05/2014
2Aromatase (CYP19)IBA
08/2017 - 10/2010
2rutecarpineIBA
08/2017 - 12/2009
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
08/2017 - 01/2009
2TriterpenesIBA
02/2016 - 12/2002
2GinsenosidesIBA
04/2015 - 06/2013
2AllergensIBA
03/2015 - 02/2015
2LigandsIBA
10/2014 - 05/2014
2Metformin (Glucophage)FDA LinkGeneric
10/2014 - 09/2013
2p38 Mitogen-Activated Protein KinasesIBA
09/2014 - 04/2011
2Heme Oxygenase-1IBA
07/2014 - 09/2013
2EnzymesIBA
11/2013 - 10/2010
2AntioxidantsIBA
06/2013 - 12/2011
2Capsaicin (Zostrix)FDA Link
11/2011 - 04/2011
2Antineoplastic Agents (Antineoplastics)IBA
05/2011 - 05/2010
2Matrix Metalloproteinase 9 (Gelatinase B)IBA
04/2011 - 10/2010
2Type I DNA Topoisomerases (Topoisomerase I)IBA
05/2010 - 07/2007
1Cytochrome P-450 CYP1A2 (CYP1A2)IBA
01/2021
1crocinIBA
10/2020
1trans-sodium crocetinate (crocetin)IBA
10/2020
1Botulinum Toxins (Botulinum Toxin)IBA
07/2020
1Dextran SulfateIBA
12/2019
1Tacrolimus (Prograf)FDA LinkGeneric
12/2019
1PolymersIBA
12/2019
1PoisonsIBA
12/2019
1Type II DNA Topoisomerases (Topoisomerase II)IBA
12/2019
1Cyclooxygenase InhibitorsIBA
09/2019
1loxoprofen (CS 600)IBA
09/2019
1Peroxidase (Myeloperoxidase)IBA
05/2018
1TI-1-162IBA
05/2018
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
05/2018
1Choline (Choline Chloride)IBA
01/2018
1Methionine (L-Methionine)FDA Link
01/2018
1Aromatase InhibitorsIBA
08/2017
1AlkaloidsIBA
08/2017
1Estradiol (Delestrogen)FDA LinkGeneric
08/2017
1Estrogens (Estrogen)FDA Link
08/2017
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
08/2017
1Sweetening Agents (Sweeteners)IBA
01/2017
1Betulinic AcidIBA
02/2016
1Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
02/2016
1usnic acidIBA
01/2016
1Protein Kinases (Protein Kinase)IBA
04/2015
1Adenosine Monophosphate (AMP)IBA
04/2015
1Sirtuin 1IBA
04/2015
1platyconic acidIBA
02/2015
1OvalbuminIBA
02/2015
1ChangkilIBA
02/2015
1aceclofenacIBA
01/2015
1Analgesics (Analgesic Drugs)IBA
01/2015
1Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
10/2014
1XenobioticsIBA
10/2014
1Death Domain ReceptorsIBA
09/2014
1Caspase 8 (Caspase-8)IBA
09/2014

Therapy/Procedure

2Therapeutics
01/2016 - 09/2013
1Microspheres (Microsphere)
12/2019